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Synlett 1994; 1994(2): 147-148
DOI: 10.1055/s-1994-22772
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Enantioselective Synthesis of Both Diastereomers Including α-Alkoxy-β-hydroxy-β-methyl Units

Shū Kobayashi* , Mineko Horibe
  • *Department of Applied Chemistry, Faculty of Science, Science University of Tokyo (SUT) Kagurazaka, Shinjuku-ku, Tokyo 162, Japan
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Publication Date:
22 March 2002 (online)

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Diastereo- and enantioselective synthesis of both diastereomers including α-alkoxy-β-hydroxy-β-methyl (AHM) units was attained by using a chiral tin(II) Lewis acid-mediated asymmetric aldol reaction of α-alkoxy silyl enol ethers with α-ketoesters.

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