Synthesis 1993; 1993(11): 1083-1085
DOI: 10.1055/s-1993-26004
short paper
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A New and Efficient Synthesis of α-Bromoalkyl Perfluoroalkyl Ketones via Opening of Epoxides

Farid Benayoud* , Jean-Pierre Bégué, Danièle Bonnet-Delpon, Nathalie Fischer-Durand, Hamid Sdassi
  • *CNRS-BIOCIS, Centre d'études Pharmaceutiques, 5 rue J. B. Clément, F-92296 Châtenay-Malabry, France
Further Information

Publication History

Publication Date:
29 April 2002 (online)

Regioselective ring opening of various substituted perfluoroepoxy ethers was achieved with magnesium bromide, leading to new α-bromofluoroalkyl ketones in good yields.