PDF herunterladen
Synlett 1993; 1993(10): 785-787
DOI: 10.1055/s-1993-22609
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Diastereodivergent Formation of 2,3-trans:3,4-cis- and 2,3-cis:3,4-trans-2,3,4-Trisubstituted Tetrahydrofurans from the Common 2,5-Disubstituted-4,5-dihydro-1,3-dioxepin: A Diastereocontrolled Route to Furofuran Lignan (±)-Asarinin

Seiichi Takano* , Kiyohiro Samizu, Kunio Ogasawara
  • *Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980, Japan
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
19. März 2002 (online)

 als PDF herunterladen  Lizenzen und Reprints Alle Artikel dieser Rubrik

Both 2,3-trans:3,4-cis- and 2,3-cis:3,4-trans-2,3,4-trisubstituted tetrahydrofurans can be generated in diastereoselective manners from the common 2,5-disubstituted-4,5-dihydro-1,3-dioxepin by selecting appropriate acid conditions. Exploiting the present finding diastereoselective route to a furofuran lignan (±)-asarinin has been developed.