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Synthesis 1992; 1992(7): 697-701
DOI: 10.1055/s-1992-26203
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4(3H)-Quinazolinones from the Reaction of N-Arylnitrilium Salts with Isocyanates

Mahmoud Al-Talib* , Johannes C. Jochims, Atef Hamed, Quanrui Wang, Abd El-Hamid Ismail
  • *Yarmouk University, Department of Chemistry, Irbid, Jordan
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Publication Date:
17 September 2002 (online)

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N-Arylnitrilium salts 1 react with isocyanates 2 to give salts 3 of 4(3H)-quinazolinones 4, from which compounds 4 can be obtained with base. A metathesis of an isocyanate with a nitrilium salt is reported.