Download PDF
Synthesis 1992; 1992(3): 328-332
DOI: 10.1055/s-1992-26102
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

An Efficient Synthesis of Symmetric Bilindiones. Mesobilirubin-Xlllα and Analogs with Varying Alkanoic Acid Chain Lengths

David P. Shrout* , Gisbert Puzicha, David A. Lightner
  • * Department of Chemistry, University of Nevada, Reno, Nevada 89557-0020, USA
Further Information

Publication History

Publication Date:
17 September 2002 (online)

 PDF Download  Permissions and Reprints All articles of this category

An inexpensive gram-scale, three-step procedure is described to convert methyl xanthobilirubinate and it alkanoic acid ester analogs (methyl 5-[(3-ethyl-1, 5-dihydro-4-methyl-5-oxo-2H-pyrrol-2-ylidene)methyl]-1, 4-dimethylpyrrol-3-ethanoate, -propanoate, -butanoate, -pentanoate, -hexanoate) into mesobilirubin-XIIIα and analogs in > 90% yield at each step.