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Synlett 1992; 1992(12): 997-998
DOI: 10.1055/s-1992-21561
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Microbial Oxidation in Synthesis: Preparation of a Potential Insulin Mimic from Benzene

Steven V. Ley* , Lam Lung Yeung
  • *Department of Chemistry, Imperial College of Science, Technology and Medicine, London SW7 2AY, England
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Publication Date:
08 March 2002 (online)

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The synthesis of 6-O-(2-amino-2-deoxy-α-D-glucopyranosyl)-1-O-dihydrogenphosphoryl-D-myo-inositol 1 as a putative insulin mimic is reported, using a microbial oxidation of benzene as an important step to provide the necessary starting material 2.