Carboxalkylation of Enolates with Menthyl Chloroformate. Diastereoselective Formation of Quaternary Carbon Centers

Werner Trypke; Alois Steigel; Manfred Braun

doi:10.1055/s-1992-21506

Subscribe to RSS

Please copy the URL and add it into your RSS Feed Reader.

https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000083.xml

Share / Bookmark

Facebook Linkedin Weibo

Download PDF

Synlett 1992; 1992(10): 827-829
DOI: 10.1055/s-1992-21506

letter

© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Carboxalkylation of Enolates with Menthyl Chloroformate. Diastereoselective Formation of Quaternary Carbon Centers

Werner Trypke^* , Alois Steigel, Manfred Braun

^*Institut für Organische Chemie und Makromolekulare Chemie, Universität Düsseldorf, Universitätsstr. 1, D-4000 Düsseldorf 1, Germany

Further Information

Publication History

Publication Date:
08 March 2002 (online)

PDF Download Permissions and Reprints All articles of this category

Diastereomeric rations of 90 : 10 to > 95 : 5 are reached when carboxylic acid, ketone, and ester-derived enolates 2, 7a/7b, 10, and 13 are allowed to react with (-)-menthyl chloroformate 1 to deliver nonracemic compounds which contain stereogenic quaternary carbon centers.