Synlett 1992; 1992(8): 679-680
DOI: 10.1055/s-1992-21456
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A Tandem Cyclisation for the Stereoselective Construction of Fused Tetracyclic Systems as Precursors of Indole Alkaloids

Julian J. Jenkinson* , Philip J. Parsons, S. C. Eyley
  • *Department of Chemistry, University of Reading, Whiteknights, P.O. Box 224, Reading, Berkshire RG6 2AD, England
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Publication History

Publication Date:
08 March 2002 (online)

A simple and stereoselective synthesis of 1,3,4,4a,5,5a,6, 11a-octahydro-5-tert-butyldimethylsiloxy-1-methoxycarbonyl-6-methyl-2H-pyrido[3, 2-b]carbazole (2) and analogues, which are precursors towards the quebrachidine group of alkaloids, is presented which relies on a linear tandem radical cyclisation.