Download PDF
Synlett 1992; 1992(7): 563-564
DOI: 10.1055/s-1992-21415
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

1,2-Heteroannulation of Lactams: A Facile Entry to Fused Pyrimidines

José Barluenga* , Miguel Tomás, Vladimir Kouznetsov, Eduardo Rubio
  • *Departamento de Química Organometálica, Facultad de Química, Universidad de Oviedo, E-33071 Oviedo, Spain
Further Information

Publication History

Publication Date:
08 March 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

Semicyclic aminoazadienes 3-4 are prepared from cyclic imines 1-2 and nitriles, and undergo cyclocondensation with aldehydes to give pyrido[1,2-c]pyrimidine 5 and pyrimido[1,6- a]azepine 6 derivatives. The preparation of fused pyrimidin-2(1H)-ones 7-8, either from azadienes 3-4 or from imines 1-2 in a one-pot procedure, is also described.

      >