Synthesis 1991; 1991(11): 993-995
DOI: 10.1055/s-1991-26626
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Coupling of Arylboronic Acids with a Partially Reduced Pyridine Derivative

David J. Wustrow* , Lawrence D. Wise
  • *Parke-Davis Pharmaceutical Research Division, Warner-Lambert Company, 2800 Plymouth Rd., Ann Arbor, MI 48106-1047, USA
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
29. April 2002 (online)

Preview

tert-Butylcarbonyl 1,2,3,6-tetrahydro-4-[(trifluoromethyl)sulfonyloxy]pyridine-1-carboxylate (2) was prepared and underwent palladium-catalyzed coupling reactions with a variety of substituted arylboronic acids 3 to produce a series of tert-butyl-4-aryl-1,2,3, 6-tetrahydropyridine-1-carboxylates 4.