PDF herunterladen
Synthesis 1991; 1991(5): 371-374
DOI: 10.1055/s-1991-26468
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Intramolecular Addition of Hydroxy Group to a Diene System: Oxymercuration - Demercuration and Titanium Tetrachloride Catalyzed Synthesis of Manoyl Oxides

Yolanda Amate* , Andrés García-Granados, Francisco A. López, Antonio Sáenz de Buruaga
  • *Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Granada, E-18071 Granada, Spain
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
29. April 2002 (online)

 als PDF herunterladen  Lizenzen und Reprints Alle Artikel dieser Rubrik

The stereochemistry of the formation of tetrahydropyran ring of ent-manoyl oxides from ent-8α-hydroxylabda-13(16), 14-dienes has been studied in one and two-step oxymercuration-demercuration (OM-DM) processes as well as by a new titanium tetrachloride catalyzed cyclization which allows the preparation of this tetrahydropyran moiety of C-13 epimer manoyl oxides in high yield.