PDF herunterladen
Synthesis 1991; 1991(5): 353-354
DOI: 10.1055/s-1991-26463
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Synthesis of Bridgehead Derivatives; 2. Preparation of 1-Substituted Bicyclo[2.2.1]heptanes

A. García Martínez* , E. Teso Vilar, J. Coterón López, J. Manrique Alonso, M. Hanack, L. R. Subramanian
  • *Departamento de Química Organíca, Facultad de Ciencias Químicas, Universidad Complutense, Ciudad Univeresitaria, E-28040 Madrid, Spain
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
29. April 2002 (online)

  als PDF herunterladen  Lizenzen und Reprints Alle Artikel dieser Rubrik

The reaction of bridgehead trifluoromethanesulfonates 1- and 4-trifluoromethylsulfonyloxycamphene (1a,b) with magnesium iodide or magnesium bromide in carbon disulfide yields the corresponding halides 2 and 3. The reaction time was reduced by sonication. The 1-(2-cyanoethyl)- and 2-methoxycarbonylethyl) -camphenes 6a and 7a, and the corresponding 4-substituted analogue 6b and 7b are prepared by radical addition of 2a and 2b to methyl acrylate (4) or acrylonitrile (5), respectively.

      >