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Synthesis of Dihydro-2,3-furandiones from Diethyl Oxalate and Aldehydes Through the Action of Sodium Methoxide
29 April 2002 (online)
Dihydro-4,4-dimethyl-2,3-furandione (4e) was synthesized from diethyl oxalate, methylpropanal (1a) and formaldehyde in the presence of sodium methoxide. In a similar manner, analogs of dihydro-2,3-furandione 4 were prepared using other aldehydes.