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Synthesis 1991; 1991(4): 270-272
DOI: 10.1055/s-1991-26442
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Total Synthesis of 4-Demethoxyfeudomycinone C

Emmanuel Bertounesque* , Jean-Claude Florent, Claude Monneret
  • *URA 1387 P, Service de Chimie, Institut Curie, Section de Biologie, 26 rue d'Ulm, F-75231 Paris Cedex 05, France
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Publication Date:
29 April 2002 (online)

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A synthesis of 4-demethoxyfeudomycinone C is described from the anthraquinone approach utilizing the carbon framework of (3R, 5S)-3-hydroxy-5-hydroxymethyl-3-methyl-2-oxotetrahydrofuran. The latter is easily derived from α-D-isosaccharinic acid.