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Synthesis 1991; 1991(2): 176
DOI: 10.1055/s-1991-26411
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An Efficient Synthesis of 3-Aminocyclopent-2-en-1-one

Bharat B. Kikani* , James R. Mckee, Murray Zanger
  • *Philadelphia College of Pharmacy and Science, Department of Chemistry, Philadelphia, PA-19104, USA
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Publication Date:
27 September 2002 (online)

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A two step, efficient synthesis of the key intermediate 3-aminocyclopent-2-en-1-one starting from 1,3-cyclopentanedione is described. This involves the reaction of ammonia gas with 3-ethoxycyclopent-2-en-1-one.

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