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Synthesis 1991; 1991(2): 141-146
DOI: 10.1055/s-1991-26399
DOI: 10.1055/s-1991-26399
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© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved.
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data processing and storage.Synthesis and Spectroscopic Properties of Azaglutamine Amino Acid and Peptide Derivatives
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Publikationsdatum:
27. September 2002 (online)
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tert-Butyl carbazate and Boc-amino acid hydrazides undergo a Michael addition with acrylamide to give substituted carbazates having the side-chain of glutamine on nitrogen. These carbazates may react with chloroformates to give protected azaglutamine esters, and N-activated amino acid esters to give azaglutamine peptides.