Download PDF
Synlett 1991; 1991(9): 649-650
DOI: 10.1055/s-1991-20828
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Anionic Hetero[3,3] Rearrangements. N-Acylhydroxylamine-O-carbamates to α-Amino Acids: A New Method for Introduction of Amino Groups at the α-Position of Carboxylic Acids

Yasuyuki Endo* , Shoji Hizatate, Koichi Shudo
  • *Faculty of Pharmaceutical Sciences, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113, Japan
Further Information

Publication History

Publication Date:
07 March 2002 (online)

 PDF Download  Permissions and Reprints All articles of this category

N-Acylhydroxylamine-O-carbamates rearrange under basic conditions to afford α-amino acid amide derivatives. The rearrangement, which can be rationalized in terms of [3,3] sigmatropic shifts, is applicable to α-amination of carboxylic acids.