Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000083.xml
Synlett 1991; 1991(1): 49-51
DOI: 10.1055/s-1991-20625
DOI: 10.1055/s-1991-20625
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.
Development of a New Six-Membered Chelating Chiral [Bisphosphine] rhodium Catalyst and Efficient Asymmetric Hydrogenation of (Z)-2-Acetamidocinnamic Acid1
Further Information
Publication History
Publication Date:
07 March 2002 (online)
A new 1,3-substituted bisphosphine ligand, (1R, 2R)-1- diphenylphosphino - 2- (diphenylphosphinomethyl) - cyclopentane (R,R)-PPCP, was prepared in four steps from ethyl 2-oxocyclopentanecarboxylate. (R,R)-PPCP was designed to form the favorable skew conformation of the six-membered chelate with rhodium. Its rhodium complex was found to be one of the most efficient catalysts for asymmetric catalytic hydrogenation of amino acid precursors such as (Z)-2-acetamidocinnamic acid.