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Synlett 1990; 1990(7): 419-420
DOI: 10.1055/s-1990-21113
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Reduction of Organic Compounds with Sodium Borohydride-Copper(II) Sulfate System

Sung-eun Yoo* , Sang-hee Lee
  • *Korea Research Institute of Chemical Technology, P.O. Box 9, Daedeog Danji, Chungnam, South Korea
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Publication Date:
08 March 2002 (online)

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The reduction of various functional groups was investigated using sodium borohydride-copper(II) sulfate. Ketones, aliphatic esters, olefins, nitriles and aliphatic and aromatic nitro groups were reduced, but amides, aliphatic and aromatic carboxylic acids wre inert. Rate of reaction was different for the various functional groups, allowing selective reductions to be performed.