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Synlett 1990; 1990(3): 159-160
DOI: 10.1055/s-1990-21020
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Microbial Oxidation of Chloroaromatics in the Enantioselective Synthesis of Carbohydrates: L-Ribonic γ-Lactone

Tomas Hudlicky* , John D. Price
  • *Department of Chemistry, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA
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Publication Date:
08 March 2002 (online)

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L-Ribonic γ-Lactone 2 has been prepared in five steps from chlorobenzene. The key reaction is the microbial oxidation of chlorobenzene by Pseudomonas putida to afford chiral cyclohexadiendiol 6.

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