Synlett 1989; 1989(1): 36-37
DOI: 10.1055/s-1989-34706
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Generation of Ketenes From Carboxylic Acids Using the Mukaiyama Reagent (1-Methyl-2-chloropyridinium Iodide)

Raymond L. Funk* , Matthew M. Abelman, Kay M. Jellison
  • *Department of Chemistry, University of Nebraska, Lincoln, Nebraska 68588-0304 and Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
Further Information

Publication History

Publication Date:
26 February 2002 (online)

Ketenes can be generated by treatment of carboxylic acids with 1-methyl-2-chloropyridinium iodide and triethylamine and may be intermediates during macrolactonization reactions via the Mukaiyama procedure. A new procedure for the direct conversion of enoic acids to [2+2] ketene-olefin cycloadducts is described.