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Synthesis 1989; 1989(11): 875-876
DOI: 10.1055/s-1989-27420
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A Facile Synthesis of 6-Methoxy-2-oxo-2,3-dihydrobenzoxazole

Dieter Sicker*
  • *Sektion Chemie der Karl-Marx-Universität Leipzig, Talstraße 35, DDR-7010 Leipzig, German Democratic Republic
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Publication Date:
02 May 2002 (online)

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A new two-step synthesis of 6-methoxybenzoxazolin-2(3H)-one, a bioactive natural product from Gramineae, is described. The new procedure avoids disadvantages of hitherto existing methods and affords the title compound in 75% overall yield from 5-methoxy-2-nitrophenol.