Synthesis 1989; 1989(8): 610-612
DOI: 10.1055/s-1989-27332
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Selective Esterification of 1,4:3,6-Dianhydro-D-glucitol

Živorad Čeković* , Zorana Tokić
  • *Department of Chemistry, Faculty of Sciences, University of Belgrade, Studentski trg 16, P.O. Box 550 YU-11001 Belgrade, and Faculty of Pharmacy, Belgrade, Yugoslavia
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Publication History

Publication Date:
17 September 2002 (online)

Esterification of 1,4:3,6-dianhydro-D-glucitol (1) with carboxcylic acids in the presence of 4-dimethylaminopyridine and dicyclohexylcar- bodiimide affords 2-exo-acylates 3 with high regioselectivity, in addition to small amounts of the isomeric 5-endo-acylates 4 and 2,5-diacylates 5.

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