Download PDF
Synthesis 1989; 1989(7): 544-547
DOI: 10.1055/s-1989-27312
communication
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Esterification of Amino Acids as Their 2,2-Bis(ethoxy-carbonyl)vinyl Derivatives

Manuel Alaiz* , Julio Girón, Francisco Javier Hidalgo, María Pilar de la Maza, Francisco Millán, Rosario Zamora, Eduardo Vioque
  • *Instituto de la Grasa y sus Derivados (C.S.I.C.), Apartado 1078, E-41012 Sevilla, Spain
Further Information

Publication History

Publication Date:
17 September 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

A method to protect the amino group of the amino acids using diethyl (ethoxymethylene)malonate is described. The resulting derivatives are easily esterified with different alkylation agents. Elimination of the N-protecting group with bromine in chloroform affords the hydrobromides of the amino acid esters.

      >