Synthesis 1989; 1989(6): 443-444
DOI: 10.1055/s-1989-27280
communication
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Ureas from N-Chloroamidines; An Aza-Analogous Hofmann Degradation

Helmut Sonnenschein* , Ernst Schmitz
  • *Central Institute of Organic Chemistry of the Academy of Sciences of the GDR, Rudower Chaussee 5, DDR-1199 Berlin, German Democratic Republic
Further Information

Publication History

Publication Date:
17 September 2002 (online)

N-Chlorination and subsequent treatment with alkali of suitably substituted benzamidines yields ureas with phenyl or alkyl migration. Under the same conditions, 2-iminopyrrolidine is converted into 2-oxohexahydropyrimidine with ring enlargement.