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Synthesis 1988; 1988(9): 707-709
DOI: 10.1055/s-1988-27680
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A Convenient Procedure for the Synthesis of Propargyl Ethers Derived from Secondary Alcohols

Carme Almansa* , Albert Moyano, Miquel A. Pericàs, Fèlix Serratosa
  • *Departament de Química Orgànica, Divisió de Ciències Experimentals i Matemàtiques, Universitat de Barcelona, Martí i Franquès 1-11, E-08028 Barcelona, Spain
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Publication Date:
18 September 2002 (online)

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A new and efficient two-step synthesis of propargyl ethers derived from secondary alcohols, involving the formation of 1-propynyl ethers followed by isomerization with potassium 3-aminopropylamide, is described. The process is insensitive to the steric hindrance of the starting alcohol.

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