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Synthesis 1988; 1988(7): 566-568
DOI: 10.1055/s-1988-27643
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Nitrosations in Anhydrous Trifluoroacetic Acid Media: A Modification for Insoluble or Deactivated Amine and Amide Precursors

K. Kanakarajan* , Karl Haider, Anthony W. Czarnik
  • *Department of Chemistry, The Ohio State University, Columbus, Ohio 43210, USA
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Publikationsdatum:
18. September 2002 (online)

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Nitrosation reactions with sodium nitrite can be accomplished cleanly in anhydrous trifluoroacetic acid as solvent, which permits the use of both deactivated and insoluble primary amines and amides as starting materials.