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Synthesis 1987; 1987(12): 1119-1121
DOI: 10.1055/s-1987-28192
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An Improved Method for the Synthesis of N 3-Benzoylthymidine

Mitsuo Sekine* , Mitsuo Fujii, Hajime Nagai, Tsujiaki Hata
  • *Department of Life Chemistry, Tokyo Institute of Technology, Nagatsuta, Midoriku, Yokohama 227, Japan
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Publication Date:
20 August 2002 (online)

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N 3-Benzoylthymidine (2), a key intermediate for oligodeoxyribonucleotide synthesis, was synthesized in high yield via 3′, 5′-bis-O-(trimethylsilyl)-N 3-benzoylthymidine, which could be isolated as stable crystals.

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