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Synthesis 1987; 1987(9): 810-811
DOI: 10.1055/s-1987-28080
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Use of Substituted Acetamides for the Synthesis of 3-Substituted 2-Aminoquinolines

Mahendra D. Chordia* , Sanjay N. Karmarkar, Shriniwas L. Kelkar, Murzban S. Wadia
  • *Department of Chemistry, University of Poona, Poona-411007, India
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Publication Date:
12 September 2002 (online)

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A novel two-step conversion of 2-aminobenzaldehydes to 3-substituted 2-diethylaminoquinolines utilizes a modified Friedländer reaction in which a substituted acetamide is used, for the first time, as a source of the C2 unit.

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