A Facile Synthesis of Dialkyl Cyclopropane-1,1-dicarboxylates and Alkyl 1-Cyanocyclopropanecarboxylates by Phase-Transfer Alkylation

József Heiszman; István Bitter; Kálmán Harsányi; László Töke

doi:10.1055/s-1987-28069

Synthesis 1987; 1987(8): 738-739
DOI: 10.1055/s-1987-28069

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A Facile Synthesis of Dialkyl Cyclopropane-1,1-dicarboxylates and Alkyl 1-Cyanocyclopropanecarboxylates by Phase-Transfer Alkylation

József Heiszman^* , István Bitter, Kálmán Harsányi, László Töke

^*Department of Organic Chemical Technology, Technical University, Budapest, 1521 Budapest, Hungary

Abstract

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The efficient syntheses of dialkyl cyclopropane- 1,1-dicarboxylates and alkyl 1-cyanocyclopropanecarboxylates; by alkylation of dialkyl malonates and alkyl cyaroacetates with 1,2-dihaloethanes are described. The importance of a certain amount of water under the solid-liquid phase-transfer conditions is demonstrated in the reactions.

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