Reactions of Sodium Borohydride in Acidic Media; XVI.1 N-Methylation of Amines with Paraformaldehyde/Trifluoroacetic Acid

Gordon W. Gribble; Charles F. Nutaitis

doi:10.1055/s-1987-28053

Subscribe to RSS

Please copy the URL and add it into your RSS Feed Reader.

https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000084.xml

Share / Bookmark

Facebook X Linkedin Weibo

Download PDF

Synthesis 1987; 1987(8): 709-711
DOI: 10.1055/s-1987-28053

communication

© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Reactions of Sodium Borohydride in Acidic Media; XVI.¹ N-Methylation of Amines with Paraformaldehyde/Trifluoroacetic Acid

Gordon W. Gribble^* , Charles F. Nutaitis

^*Department of Chemistry, Dartmouth College, Hanover, NH 03755, U.S.A.

Further Information

Publication History

Publication Date:
12 September 2002 (online)

PDF Download Permissions and Reprints All articles of this category

Primary and secondary amines are N-methylated to afford tertiary amines with the combination of paraformaldehyde, sodium borohydride, and trifluoroacetic acid.

>