Synthesis 1987; 1987(5): 495-496
DOI: 10.1055/s-1987-27981
communication
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

A Simple Synthesis of 5-(1-Alkenyl)uracil Derivatives by Palladium-Catalyzed Oxidative Coupling of Uracils With Olefins

Kosaku Hirota* , Yoshiaki Isobe, Yukio Kitade, Yoshifumi Maki
  • *Gifu Pharmaceutical University, Mitahora-Higashi, Gifu 502, Japan
Further Information

Publication History

Publication Date:
18 September 2002 (online)

The oxidative coupling of uracil derivatives t with olefins, such as methyl acrylate, acrylonitrile, methyl vinyl ketone, and styrene, using one equivalent of palladium acetate leads to the corresponding 5-(1-alkenyl)uracil derivatives 2.

    >