Synthesis 1986; 1986(7): 567-569
DOI: 10.1055/s-1986-31707
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An Easy Conversion of 2H-Chromenes into Coumarins. An Entry to 3-Formyl Coumarins

Loïc Rene* , Alain Lefebvre, Gilles Auzou
  • *INSERM U 98, 17 rue du Fer à Moulin, F-75005 Paris, France
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Publication History

Publication Date:
20 August 2002 (online)

3-Formyl coumarins 4 are easily prepared by conversion of 3-cyano-2-morpholino-2H-chromenes 1 in boiling aqueous hydrochloric acid.This transformation occurs in two steps from salicylaldehydes.

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