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Synthesis 1986; 1986(5): 430-431
DOI: 10.1055/s-1986-31668
DOI: 10.1055/s-1986-31668
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Synthesis of 10-Alkylthio- and Arylthio-1,8-Dihydroxy-9-anthrones, A New Class of Anthracene Derivatives of Potential Pharmacological Interest
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Publication Date:
27 September 2002 (online)
The synthesis of some representative 10-alkylthio- and 10-arylthio-1, 8-dihydroxy-9-anthrones, a new class of anthracene derivatives of potential pharmacological interest, is described, involving acid-catalyzed reaction of 1,8,10-trihydroxy-9-anthrone with a thiol at room temperature. The easy availability of all intermediates and the mild reaction conditions render the method simple and of general application.