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Synthesis 1986; 1986(4): 301-303
DOI: 10.1055/s-1986-31590
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A New Synthesis of 2-Aminoalcohols from O-Trimethylsilylated Cyanohydrins

Larry R. Krepski* , Karen M. Jensen, Steven M. Heilmann, Jerald K. Rasmussen
  • *Central Research Laboratories, 3M Company, 3M Center, St. Paul, Minnesota 55144, U. S. A.
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Publication Date:
27 September 2002 (online)

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The reaction of O-trimethylsilylated cyanohydrins with Grignard reagents, followed by reduction, represents a convenient synthesis of 2-aminoalcohols.