Subscribe to RSS

DOI: 10.1055/s-0045-1801870
Surgical Alternative for Multiple Pilar Cutaneous Leiomyoma of the Lower Limb: Case Report and Literature Review
Article in several languages: português | English Financial Support The authors declare that they did not receive financial support from agencies in the public, private or non-profit sectors to conduct the present study.Ensaios Clínicos Não. | Clinical Trials None.

Abstract
Pilar leiomyoma, or benign neoplasia of the arrector pili muscles, is an uncommon pathology, although it is the most frequent type of cutaneous leiomyoma. It occurs in young adults, affecting both sexes equally. It presents as multiple or isolated, reddish-brown, papulonodular lesions. Although no malignant tumors have been reported, it is important to include this pathology in the differential diagnosis of papulonodular cutaneous lesions. Surgical treatment is often reserved for prolonged and symptomatic cases, with relapse reports. In this paper, we report the case of a 28-year-old male patient with a diagnosis of pilar leiomyoma on the lateral thigh and right leg who underwent a tangential skin resection.
Author's Contributions
IMS: analysis and/or interpretation of data, validation, and writing – original draft; ASC: supervision; LAA: formal analysis; LVD, methodology; MSV, data curation; and SFAG: writing – original draft.
Publication History
Received: 04 October 2023
Accepted: 29 September 2024
Article published online:
11 February 2025
© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)
Thieme Revinter Publicações Ltda.
Rua do Matoso 170, Rio de Janeiro, RJ, CEP 20270-135, Brazil
Igor Moura Soares, Armando dos Santos Cunha, Lucas Albuquerque Aquino, Lucas Vargas Dalbosco, Marcela Santos Vilela, Saulo Francisco de Assis Gomes. Alternativa cirúrgica para leiomioma cutâneo pilar múltiplo de membro inferior: Relato de caso e revisão da literatura. Revista Brasileira de Cirurgia Plástica (RBCP) – Brazilian Journal of Plastic Surgery 2024; 39: s00451801870.
DOI: 10.1055/s-0045-1801870
-
Referências
- 1 Martinez-Mir A, Gordon D, Horev L. et al. Multiple cutaneous and uterine leiomyomas: refinement of the genetic locus for multiple cutaneous and uterine leiomyomas on chromosome 1q42.3-43. J Invest Dermatol 2002; 118 (05) 876-880
- 2 White LE, Levy RM, Alam M. Neoplasias and hyperplasias of muscular and neural origin. In: Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ, Wolff K. , editors. Fitzpatrick's dermatology in general medicine. 8th ed. Vol. 1. New York: McGraw-Hill; 2012. . p. 1470–1.
- 3 Virchow R. Ueber Makroglossie und pathologische Neubildung quergestreifter Muskelfasern. Virchows Arch Pathol Anat. 1854; 7: 126-138
- 4 Lun KR, Spelman LJ. Multiple piloleiomyomas. Australas J Dermatol 2000; 41 (03) 185-186
- 5 Alam NA, Barclay E, Rowan AJ. et al. Clinical features of multiple cutaneous and uterine leiomyomatosis: an underdiagnosed tumor syndrome. Arch Dermatol 2005; 141 (02) 199-206
- 6 Makino E, Yamada J, Tada J, Arata J, Iwatsuki K. Cutaneous angiolipoleiomyoma. J Am Acad Dermatol 2006; 54 (01) 167-171
- 7 Kudur MH. A generalized multiple cutaneous piloleiomyomatosis in a young male: rare case report. Indian J Dermatol 2013; 58 (03) 245
- 8 Launonen V, Vierimaa O, Kiuru M. et al. Inherited susceptibility to uterine leiomyomas and renal cell cancer. Proc Natl Acad Sci U S A 2001; 98 (06) 3387-3392
- 9 Matoso A, Chen S, Plaza JA, Osunkoya AO, Epstein JI. Symplastic leiomyomas of the scrotum: a comparative study to usual leiomyomas and leiomyosarcomas. Am J Surg Pathol 2014; 38 (10) 1410-1417
- 10 Idriss MH, Kazlouskaya V, Malhotra S, Andres C, Elston DM. Phosphohistone-H3 and Ki-67 immunostaining in cutaneous pilar leiomyoma and leiomyosarcoma (atypical intradermal smooth muscle neoplasm). J Cutan Pathol 2013; 40 (06) 557-563
- 11 Holst VA, Junkins-Hopkins JM, Elenitsas R. Cutaneous smooth muscle neoplasms: clinical features, histologic findings, and treatment options. J Am Acad Dermatol 2002; 46 (04) 477-490 , quiz, 491–494
- 12 Ghanadan A, Abbasi A, Kamyab Hesari K. Cutaneous leiomyoma: novel histologic findings for classification and diagnosis. Acta Med Iran 2013; 51 (01) 19-24
- 13 Aggarwal S, De D, Kanwar AJ, Saikia UN, Khullar G, Mahajan R. Disseminated cutaneous leiomyomatosis treated with oral amlodipine. Indian J Dermatol Venereol Leprol 2013; 79 (01) 136