Effect of the Application of Different High-Definition (HD) Colonoscopy Systems Combined With Virtual Chromoendoscopy on the Adenoma Detection Rate – a Non-Inferiority Pilot Study

Aims We aimed to evaluate adenoma detection rate (ADR) in consecutive patients investigated with the HD colonoscopy system of AOHUA and to compare the results to our previous colonoscopy series performed with HD FUJIFILM colonoscopy system.

Methods We analyzed consecutive colonoscopy results with AOHUA-AQ200 system (polyp detection was supported with Hemoglobin Enhancement and polyp delineation with Compound Band Imaging) between March 2020 and October 2020 and FUJIFILM-7000 Eluxeo endoscopy system (polyp detection was supported with Linked Colour Imaging and polyp delineation with Blue Light Imaging) between October 2016 and June 2018, performed by the same three expert endoscopists in our Endoscopy Unit. Results in ADR was compared by the Chi-square test, and the predictors of ADR were estimated using logistic regression test with sex, age as independent variables.

Results Total 265 colonoscopies (132 male (49.8 %); mean age: 52.6 years, SD: 14 years) were performed using AOHUA, and 1620 colonoscopies were performed with FUJIFILM (842 male (52 %); mean age: 51.7 years, SD: 13.6 years) during the study period. Using AOHUA, overall ADR was 26.4 % (70/265), above 40 year-olds was 30.8 % (68/221) and 33.3 % (53/159) above 50 year-olds. Overall ADR with FUJI system was 30.7 % (497/1620). ADR above 40 year-olds was 35.6 % (465/1306) and 40.8 % (370/906) above 50 year-olds. Comparing the results with different colonoscope technologies but the same operators, we demonstrated no significant difference between ADR (OR 0.86; 95 %CI 0.66-1.17; p=0.39). Sex and age were independent predictors of ADR. In the adjusted model, male sex and age also increased the odds of ADR but did not alter the difference (OR 0.84, p = 0.24).

Conclusions Our results with the HD colonoscopy system by AOHUA combined with virtual chromoendoscopy proved to be non-inferior in ADR comparing to HD FUJIFILM system. Further prospective randomized studies are required to confirm our results.

Citation: Lovasz BD, Finta A, Szalai M et al. eP209 EFFECT OF THE APPLICATION OF DIFFERENT HIGH-DEFINITION (HD) COLONOSCOPY SYSTEMS COMBINED WITH VIRTUAL CHROMOENDOSCOPY ON THE ADENOMA DETECTION RATE – A NON-INFERIORITY PILOT STUDY. Endoscopy 2021; 53: S167.

Publication History

Article published online:
19 March 2021