Facile Construction of Troponoid Derivatives Incorporating Imidazolin-2-one Moieties

Jing Yu; Xiaobei Chen; Ye Liu; Bing Wu; Haiyan Li; Yanwei Hu; Liang Wang; Shilei Zhang

doi:10.1055/s-0040-1708006

Synthesis, Inhaltsverzeichnis

Synthesis 2020; 52(12): 1847-1854
DOI: 10.1055/s-0040-1708006

paper

Facile Construction of Troponoid Derivatives Incorporating Imidazolin-2-one Moieties

Jing Yu‡

^aJiangsu Key Laboratory of Neuropsychiatric Diseases & College of Pharmaceutical Sciences, Soochow University, 199 Ren’ai Road, Suzhou, Jiangsu, 215123, P. R. of China eMail: huyanwei@suda.edu.cn eMail: zhangshilei@suda.edu.cn

,

Xiaobei Chen‡

^bState Key Laboratory of Bioengineering Reactor, and Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science & Technology, Shanghai 200237, P. R. of China

,

Ye Liu

^aJiangsu Key Laboratory of Neuropsychiatric Diseases & College of Pharmaceutical Sciences, Soochow University, 199 Ren’ai Road, Suzhou, Jiangsu, 215123, P. R. of China eMail: huyanwei@suda.edu.cn eMail: zhangshilei@suda.edu.cn

,

Bing Wu

^dCollege of Chemistry, Chemical Engineering and Materials Science, Soochow University, 199 Ren’ai Road, Suzhou, Jiangsu, 215123, P. R. of China

,

Haiyan Li

^dCollege of Chemistry, Chemical Engineering and Materials Science, Soochow University, 199 Ren’ai Road, Suzhou, Jiangsu, 215123, P. R. of China

,

Yanwei Hu∗

^aJiangsu Key Laboratory of Neuropsychiatric Diseases & College of Pharmaceutical Sciences, Soochow University, 199 Ren’ai Road, Suzhou, Jiangsu, 215123, P. R. of China eMail: huyanwei@suda.edu.cn eMail: zhangshilei@suda.edu.cn

,

Liang Wang∗

^cCollege of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, Qingdao 266109, P. R. of China eMail: liangwang0532@yeah.net

,

Shilei Zhang∗

^aJiangsu Key Laboratory of Neuropsychiatric Diseases & College of Pharmaceutical Sciences, Soochow University, 199 Ren’ai Road, Suzhou, Jiangsu, 215123, P. R. of China eMail: huyanwei@suda.edu.cn eMail: zhangshilei@suda.edu.cn

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Abstract

Alle Artikel dieser Rubrik

Abstract

Troponoid derivatives incorporating imidazolin-2-one moieties were efficiently constructed via a cascade process, under simple thermal conditions, which features a novel nitrogen source, is catalyst- and oxidant-free, and has high atom- and step-economy.

Key words

troponoid - isocyanate - imidazolin-2-one - cascade reaction - high temperature

Volltext

Referenzen

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25 CCDC 1821619 (4a) contains the supplementary crystallographic data for this paper. The data can be obtained free of charge from The Cambridge Crystallographic Data Centre via www.ccdc.cam.ac.uk/getstructures.

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