Gold-Catalyzed Partial Hydrogenation of Activated Alkynes Mediated by Triphenylphosphine

Abstract

Gold(I) can exhibit a cooperative effect with triphenylphosphine, accelerating the triphenylphosphine-mediated partial hydrogenation of activated alkynes. In this protocol, 3-arylpropiolates are selectively reduced to the Z-isomer when the aryl ring bears an electron-donor substituent, whereas 3-arylpropynones are reduced to the E-isomers.

Key words

partial hydrogenation - alkynes - triphenylphosphine - gold - catalysis

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