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CC BY-NC-ND 4.0 · SynOpen 2020; 04(03): 55-61
DOI: 10.1055/s-0040-1707203
DOI: 10.1055/s-0040-1707203
paper
Synthesis of Quinoxalin-2(1H)-ones and Hexahydroquinoxalin-2(1H)-ones via Oxidative Amidation–Heterocycloannulation
Authors
Dr. Krishnaji acknowledges CHRIST (Deemed to be University) for funding through a Major Research Project (MRP # MRPDSC-1723).
Further Information
Publication History
Received: 02 June 2020
Accepted after revision: 30 June 2020
Publication Date:
18 August 2020 (online)
Abstract
A metal-catalyst-free synthesis of substituted quinoxalin-2-ones from 2,2-dibromo-1-arylethanone by employing an oxidative amidation–heterocycloannulation protocol is reported. The substrate scope of the reaction has been demonstrated and a possible mechanism for this reaction has also been proposed.
Key words
oxidative amidation - heterocycloannulation - quinoxalin-2(1H)-one - 2,2-dibromo-1-arylethanoneSupporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0040-1707203.
- Supporting Information (PDF)
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