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Synlett 2020; 31(03): 261-266
DOI: 10.1055/s-0039-1691537
DOI: 10.1055/s-0039-1691537
letter
Visible-Light-Induced Arene C(sp2)–H Lactonization Promoted by DDQ and tert-Butyl Nitrite
Authors
This project was supported by the National Natural Science Foundation of China (21776260, 21773211 and 21773210) and the Natural Science Foundation of Zhejiang Province (LY17B060007).
Further Information
Publication History
Received: 01 November 2019
Accepted after revision: 27 November 2019
Publication Date:
16 December 2019 (online)
Abstract
A visible-light photocatalytic aerobic oxidative lactonization of arene C(sp2)–H bonds proceeds in the presence of 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) and tert-butyl nitrite (TBN). Under the optimized conditions, a range of 2-arylbenzoic acids is converted into the corresponding benzocoumarin derivatives in moderate to excellent yields. This method is characterized by its atom economy, mild reaction conditions, the use of a green oxidant and metal-free catalysis.
Key words
photocatalysis - lactonization - 2-arylbenzoic acids - 2,3-dichloro-5,6-dicyano-1,4-benzoquinone - oxygenSupporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0039-1691537.
- Supporting Information (PDF) (opens in new window)
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