Metal-Free 1,2,3-Triazole Synthesis in Deep Eutectic Solvents

Published as part of the ISySyCat2019 Special Issue

Abstract

The metal-free regioselective preparation of 1,5- and 1,4-disubstituted triazoles is reported through a cycloaddition–elimination sequence. Reactions were carried out in environmentally friendly deep eutectic solvent (DES) and pure products were isolated without the need for chromatographic techniques.

Key words

alkene - azide - deep eutectic solvent - triazole - triazoline - metal-free synthesis

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