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Synthesis 2019; 51(22): 4279-4283
DOI: 10.1055/s-0039-1690126
DOI: 10.1055/s-0039-1690126
paper
Straightforward and Expeditious One-Pot Tandem Synthesis of 3,5-Diaryl-1,2,4-Selenadiazoles from Aryl Nitriles
M.H.B. gratefully acknowledges financial support through the startup funds from the University of Arkansas. A.R.K. and H.Z.B. gratefully thank the Center of Excellence of Chemistry and the Research Council of the University of Isfahan (CECUI) for financial support of this work. The authors declare no competing financial interest.Weitere Informationen
Publikationsverlauf
Received: 22. Mai 2019
Accepted after revision: 25. Juni 2019
Publikationsdatum:
08. August 2019 (online)
Abstract
A one-pot process for the efficient synthesis of 3,5-diaryl-1,2,4-selenadiazoles from aryl nitriles has been developed. This tandem transformation was performed in excellent yields (91–98%) via in situ selenoamidation and a subsequent oxidative dimerization reaction. This method features relatively mild reaction conditions, operational simplicity, straightforward separation of the products, and the utilization of inexpensive reagents.
Key words
selenadiazoles - selenoamides - cyanuric chloride - dimethyl sulfoxide - oxidative dimerizationSupporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0039-1690126.
- Supporting Information
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