Synlett 2019; 30(10): 1199-1203
DOI: 10.1055/s-0039-1689934
cluster
© Georg Thieme Verlag Stuttgart · New York

Three-Component Chlorophosphinoylation of Alkenes via Anodically Coupled Electrolysis

,
Niankai Fu
,
Financial support for this work was provided by Cornell University (Division of Chemistry) and the National Science Foundation (NSF) (CHE-1751839). This study made use of the NMR facility supported by the National Science Foundation (CHE-1531632).
Further Information

Publication History

Received: 22 April 2019

Accepted after revision: 20 May 2019

Publication Date:
23 May 2019 (online)


Published as part of the Cluster Electrochemical Synthesis and Catalysis

Abstract

We report the development of an electrocatalytic protocol for the chlorophosphinoylation of simple alkenes. Driven by electricity and mediated by a Mn catalyst, the heterodifunctionalization reaction takes place with high efficiency and regioselectivity. Cyclic voltammetry data are consistent with a mechanistic scenario based on anodically coupled electrolysis in which the generation of two distinct radical intermediates occur simultaneously on the anode and are both mediated by the Mn catalyst.

Supporting Information

 
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