Am J Perinatol 2018; 35(06): 575-577
DOI: 10.1055/s-0038-1639361
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

New Diagnostic Possibilities for Neonatal Sepsis

Chryssoula Tzialla
1  Neonatology and Neonatal Intensive Care Unit, Fondazione IRCCS Policlinico “San Matteo,” Pavia, Italy
,
Paolo Manzoni
2  Neonatology and NICU, S. Anna Hospital, AOU Città della Salute e della Scienza, Torino, Italy
,
Cristian Achille
1  Neonatology and Neonatal Intensive Care Unit, Fondazione IRCCS Policlinico “San Matteo,” Pavia, Italy
,
Lina Bollani
1  Neonatology and Neonatal Intensive Care Unit, Fondazione IRCCS Policlinico “San Matteo,” Pavia, Italy
,
Mauro Stronati
1  Neonatology and Neonatal Intensive Care Unit, Fondazione IRCCS Policlinico “San Matteo,” Pavia, Italy
,
Alessandro Borghesi
1  Neonatology and Neonatal Intensive Care Unit, Fondazione IRCCS Policlinico “San Matteo,” Pavia, Italy
› Author Affiliations
Further Information

Publication History

Publication Date:
25 April 2018 (online)

Abstract

Progress in neonatal care has decrease morbidity and mortality due to neonatal sepsis (NS). Although diagnosis of sepsis continues to rely on blood culture, this method is too slow and limited by false-negative results. There are numerous sepsis biomarkers that have been evaluated for the early diagnosis of NS, but, to date, there is no single ideal biomarker, though novel biomarkers are becoming more sophisticated and specific in their clinical applications. This review provides an overview of the current diagnostic approaches available or under development for diagnosing NS.