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Methods Inf Med 2006; 45(05): 557-563
DOI: 10.1055/s-0038-1634118
Original Article
Schattauer GmbH

Deconfounding Microarray Analysis

Independent Measurements of Cell Type Proportions Used in a Regression Model to Resolve Tissue Heterogeneity Bias
M. Jacobsen*
1   Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
,
D. Repsilber*
2   Institute of Medical Biometry and Statistics, University at Lübeck, Lübeck, Germany
3   Current address: Institute for Biology and Biochemistry, University Potsdam, Potsdam-Golm, Germany
,
A. Gutschmidt
1   Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
,
A. Neher
4   Asklepios Center for Respiratory Medicine and Thoracic Surgery, Munich-Gauting, Germany
,
K. Feldmann
4   Asklepios Center for Respiratory Medicine and Thoracic Surgery, Munich-Gauting, Germany
,
H. J. Mollenkopf
5   Microarray Core Facilities, Max Planck Institute for Infection Biology, Berlin, Germany
,
S. H. E. Kaufmann
1   Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
,
A. Ziegler
2   Institute of Medical Biometry and Statistics, University at Lübeck, Lübeck, Germany
› Author Affiliations