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Synthesis 2019; 51(09): 1989-1994
DOI: 10.1055/s-0037-1612280
DOI: 10.1055/s-0037-1612280
paper
Synthesis of a Variety of Activated Pyrrolo[3,2,1-ij]quinolines
Authors
Financial support from the Australian Research Council is gratefully acknowledged (DP180100845).
Further Information
Publication History
Received: 12 November 2018
Accepted after revision: 26 January 2019
Publication Date:
28 February 2019 (online)
Abstract
A range of 7,9-dimethoxypyrrolo[3,2.1-ij]quinolines have been prepared by the cyclisation of 7-formyl-1-diethylcarbethoxyindoles. The functionality at C5 has been varied by the conversion of the carbethoxy group into carboxy, azidocarbonyl and isocyanate groups. The hydroboration of a previously reported pyrroloquinolone gave a related 5-hydroxypyrrolo[3,2,1-ij]quinolone, and the hydroxyl group was sequentially converted into tosylate, azido and amino groups.
Supporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0037-1612280.
- Supporting Information (PDF)
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