Copper-Catalyzed Three-Component Coupling Reaction of Aryl Iodides, a Disilathiane, and Alkyl Benzoates Leading to a One-Pot Synthesis of Alkyl Aryl Sulfides

Norio Sakai; Hiromu Maeda; Yohei Ogiwara

doi:10.1055/s-0037-1610869

Synthesis, Inhaltsverzeichnis

Synthesis 2019; 51(11): 2323-2330
DOI: 10.1055/s-0037-1610869

paper

Copper-Catalyzed Three-Component Coupling Reaction of Aryl Iodides, a Disilathiane, and Alkyl Benzoates Leading to a One-Pot Synthesis of Alkyl Aryl Sulfides

Norio Sakai *

Department of Pure and Applied Chemistry, Faculty of Science and Technology, Tokyo University of Science (RIKADAI), Noda, Chiba 278-8510, Japan eMail: sakachem@rs.noda.tus.ac.jp

,

Hiromu Maeda

,

Yohei Ogiwara

› Institutsangaben

Abstract

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Abstract

A copper-catalyzed three-component coupling reaction of aryl iodides, hexamethyldisilathiane and alkyl benzoates leading to alkyl aryl sulfides has been demonstrated. A disilathiane acted as both a sulfur source and a promoter of the sulfidation, and the alkyl moiety of the alkyl benzoate was effectively introduced on one side of the sulfide. Moreover, we found that the protocol can be expanded to the preparation of ethyl phenyl selenide with diphenyl diselenide.

Key words

disilathiane - alkyl benzoate - alkyl aryl sulfide - copper - coupling

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Referenzen

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