Synthesis 2020; 52(09): 1417-1424
DOI: 10.1055/s-0037-1610739
paper
© Georg Thieme Verlag Stuttgart · New York

One-Pot Copper-Catalyzed Three-Component Reaction of Sulfonyl Azides, Alkynes, and Allylamines To Access 2,3-Dihydro-1H-imi­dazo[1,2-a]indoles

Authors


This work was supported by the National Science Foundation of China­ (Grant / Award Number: 'Nos. 21772176 and 21372201').
Weitere Informationen

Publikationsverlauf

Received: 02. September 2019

Accepted after revision: 26. November 2019

Publikationsdatum:
05. Februar 2020 (online)


Graphical Abstract

Preview

Abstract

A copper-catalyzed multicomponent reaction of sulfonyl azides, alkynes, and allylamines affording 2,3-dihydro-1H-imidazo-[1,2-a]indoles in moderate yields is reported. Four C–N bonds are constructed­ by way of azide-alkyne cycloaddition (CuAAC) and double Ullmann-type coupling reactions in a one-pot process.

Supporting Information