Synthesis 2019; 51(24): 4635-4644
DOI: 10.1055/s-0037-1610729
paper
© Georg Thieme Verlag Stuttgart · New York

Divergent Synthesis of Various 2-Aryl Iminocyclitols from (R)-p-Hydroxyphenylglycine

Vipin Kumar Jain
Further Information

Publication History

Received: 05 July 2019

Accepted after revision: 02 September 2019

Publication Date:
30 September 2019 (online)

Abstract

A concise and efficient synthesis of various 2-aryl iminocyclitols is reported from (R)-p-hydroxyphenylglycine using Upjohn dihydroxylation and base-promoted intramolecular cyclization. These 2-aryl iminocyclitols are the important structural framework of various bioactive compounds and also known as glycosidase inhibitors.

Supporting Information

 
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